Stocks/Funds/CIK 1816307

SILVERARC CAPITAL MANAGEMENT, LLC

long-term holder
Quarterly 13F filings · Latest period 2026-03-31 · CIK 1816307
Assets
$843M
+85.6% YoY
Holdings
66
Lifetime alpha vs market
-0.90% annual
Average hold time
1.9 yr
median 1.5 yr

Quarterly history

Cum return +47% vs S&P +52% · α -5% lifetimeAUM $843M · peak $843MFlow $101M (+15%)2020-122021-122022-122023-122024-122025-122026-03
AUM ($B)fundS&P 500(gap = α)/ Flow in/out

Behavior signals (lifetime)

Dip response
-11.44%
trims when stocks drop
when a holding falls −10%+
Middle response
-4.64%
baseline attrition
Rally response
-1.93%
trims into rallies
when a holding rises +10%+

Top positions · 30

Ticker$ value% portYoYHold time
KALVKalVista Pharmaceuticals$58M6.9%+74.4%3.8 yr
DNTHDianthus Therapeutics, I$55M6.5%+362.6%1.3 yr
COGTCogent Biosciences, Inc.$51M6.0%+542.6%5.0 yr
CELCCelcuity Inc.$41M4.8%+1029.0%0.8 yr
IMNMImmunome, Inc.$40M4.8%+225.0%0.8 yr
KODKodiak Sciences Inc.$38M4.5%+1256.6%2.8 yr
NUVLNuvalent, Inc.$36M4.3%+44.5%3.5 yr
ABVXAbivax S.A.$34M4.0%+1681.6%2.0 yr
GLUEMonte Rosa Therapeutics,$33M3.9%+254.5%1.3 yr
ERASErasca, Inc.$30M3.6%+1081.0%2.5 yr
$29M3.4%3.3 yr
URGNUroGen Pharma Ltd.$27M3.2%+62.6%2.8 yr
RYTMRhythm Pharmaceuticals, $27M3.2%+64.2%3.0 yr
$23M2.7%2.5 yr
ZBIOZenas BioPharma, Inc.$22M2.6%+147.5%0.3 yr

Portfolio composition (YoY)

Industry mix
Biotechnology86.6%+1.5pp$730M
Unknown8.5%-2.8pp$72M
Shell Companies1.5%$12M
Drug Manufacturers - General1.1%-0.4pp$9M
Medical - Diagnostics & Research1.1%$9M
Medical - Devices0.9%-1.1pp$7M
Medical - Care Facilities0.2%$2M
Asset Management0.1%$1M
Country
US79.4%+11.6pp
Unknown8.5%-2.8pp
FR4.0%+3.7pp
GB2.4%-6.0pp
IE1.9%+1.0pp
KY1.5%
CA1.4%+1.3pp
IL0.8%-0.1pp
Top 5: 29.0% · Top 10: 49.3% · Top 25: 81.5%

Winners

TickerPrev $PnLYoY %
ERAS$10M+0.11B1081.0%
ABVX$1M+0.02B1681.6%
KOD$1M+0.02B1256.6%
ORIC$11M+0.01B127.1%
KALV$20M+0.01B74.4%

Losers

TickerPrev $PnLYoY %

Top buys this quarter · 15

ZBIO Zenas BioPharma, Inc.new+$22M
GLUE Monte Rosa Therapeutics, Inc.+$16M
IMNM Immunome, Inc.+$16M
RYTM Rhythm Pharmaceuticals, Inc.+$15M
HLXC Helix Acquisition Corp. III Clnew+$12M
XENE Xenon Pharmaceuticals Inc.+$11M
ALKS Alkermes plc+$10M
IMVT Immunovant, Inc.+$9M
KALV KalVista Pharmaceuticals, Inc.+$9M
ERAS Erasca, Inc.+$9M

Top sells this quarter · 15

ABVX Abivax S.A.$13M
CGON CG Oncology, Inc. Common stock$13M
PFE Pfizer Inc.exit$12M
CYTK Cytokinetics, Incorporated$9M
DNTH Dianthus Therapeutics, Inc.$31M
AMLX Amylyx Pharmaceuticals, Inc.exit$7M
VRDN Viridian Therapeutics, Inc.exit$7M
VCYT Veracyte, Inc.$6M
BIIB Biogen Inc.$4M
URGN UroGen Pharma Ltd.$4M

Quarterly history (TTM returns)

PeriodAUM# PosReturn (1yr)SPY (1yr)Alpha (1yr)Flow
2026-03-31$843M66+94.37%+17.59%+76.78%+0.10B
2025-12-31$679M63+43.57%+17.72%+25.85%-0.13B
2025-09-30$661M72+7.28%+17.52%-10.24%+0.02B
2025-06-30$464M56-15.28%+14.94%-30.22%-0.01B
2025-03-31$454M66-33.33%+8.30%-41.63%+0.11B
2024-12-31$422M57-4.10%+24.89%-28.99%+0.04B
2024-09-30$418M67+16.97%+36.04%-19.07%-0.01B
2024-06-30$396M65+9.90%+24.49%-14.60%+0.11B
2024-03-31$354M72+50.82%+29.62%+21.20%-0.02B
2023-12-31$324M64+20.10%+26.18%-6.07%+0.02B
2023-09-30$268M68+17.84%+21.57%-3.73%-0.04B
2023-06-30$296M77+11.69%+19.42%-7.73%+0.05B
2023-03-31$223M67-24.91%-7.82%-17.10%-0.05B
2022-12-31$290M81+9.78%+7.56%+2.22%+0.04B
2022-09-30$231M68-2.55%-4.93%+2.38%+0.03B
2022-06-30$209M58-24.14%-16.11%-8.03%+0.07B