Stocks/Funds/CIK 2018299

Boxer Capital Management, LLC

Quarterly 13F filings · Latest period 2026-03-31 · CIK 2018299
Assets
$762M
+129.1% YoY
Holdings
54
Lifetime alpha vs market
+105.61% annual
Average hold time
0.7 yr
median 0.8 yr

Quarterly history

Cum return +177% vs S&P +13% · α +165% lifetimeAUM $762M · peak $1.2BFlow $105M (+23%)2024-122025-032025-062025-092025-122026-03
AUM ($B)fundS&P 500(gap = α)/ Flow in/out

Behavior signals (lifetime)

Dip response
-29.67%
trims when stocks drop
when a holding falls −10%+
Middle response
-16.42%
baseline attrition
Rally response
-8.84%
trims into rallies
when a holding rises +10%+

Top positions · 30

Ticker$ value% portYoYHold time
TNGXTango Therapeutics, Inc.$228M29.9%+1427.0%1.5 yr
KODKodiak Sciences Inc.$52M6.8%+1256.6%1.5 yr
RVMDRevolution Medicines, In$49M6.4%+175.0%1.5 yr
KYMRKymera Therapeutics, Inc$27M3.6%+204.3%1.5 yr
CELCCelcuity Inc.$26M3.4%+1029.0%0.8 yr
$22M2.9%0.5 yr
ABVXAbivax S.A.$22M2.9%+1681.6%0.8 yr
TERNTerns Pharmaceuticals, I$20M2.6%0.8 yr
PCVXVaxcyte, Inc.$19M2.5%+53.9%0.3 yr
CAPRCapricor Therapeutics, I$18M2.4%+220.3%0.5 yr
PTGXProtagonist Therapeutics$18M2.4%+117.9%1.0 yr
VIRVir Biotechnology, Inc.$17M2.2%+38.3%0.5 yr
CRVSCorvus Pharmaceuticals, $16M2.1%+360.1%0.3 yr
$15M2.0%0.5 yr
PTCTPTC Therapeutics, Inc.$14M1.8%+33.7%0.8 yr

Portfolio composition (YoY)

Industry mix
Biotechnology90.5%-7.7pp$689M
Unknown9.5%+7.7pp$73M
Country
US84.9%+6.6pp
Unknown9.5%+7.7pp
FR2.9%
NL1.4%-9.8pp
CH0.7%
CA0.5%-5.5pp
Top 5: 50.0% · Top 10: 63.3% · Top 25: 87.2%

Winners

TickerPrev $PnLYoY %
TNGX$14M+0.20B1427.0%
RVMD$47M+0.08B175.0%
KOD$3M+0.04B1256.6%
KYMR$9M+0.02B204.3%
AMLX$6M+0.02B292.7%

Losers

TickerPrev $PnLYoY %
REPL$18M-0.00B-21.5%

Top buys this quarter · 15

PCVX Vaxcyte, Inc.new+$19M
CRVS Corvus Pharmaceuticals, Inc.new+$16M
DFTX Definium Therapeutics, Inc.new+$11M
VIR Vir Biotechnology, Inc.+$11M
IRD Opus Genetics, Inc.new+$10M
CORT Corcept Therapeutics Incorporanew+$10M
RVMD Revolution Medicines, Inc.+$10M
KOD Kodiak Sciences Inc.+$9M
ABVX Abivax S.A.+$8M
PGEN Precigen, Inc.+$8M

Top sells this quarter · 8

ORIC ORIC Pharmaceuticals, Inc.$20M
PEPG PepGen Inc.$0M
CYBN Cybin Inc.$0M
GBM.F Inovio Pharmaceuticals, Inc.$0M
CDTX Cidara Therapeutics, Inc.exit$0M
exit$0M
NUVB-WT Nuvation Bio Inc.exit$0M
exit$0M

Quarterly history (TTM returns)

PeriodAUM# PosReturn (1yr)SPY (1yr)Alpha (1yr)Flow
2026-03-31$762M54+238.53%+17.59%+220.93%+0.11B
2025-12-31$457M45+92.85%+17.72%+75.14%+0.08B
2025-09-30$314M34+59.22%+8.12%+51.10%-0.00B
2025-06-30$199M20+22.52%+10.78%+11.75%-0.21B
2025-03-31$332M28-18.13%-4.27%-13.86%-0.63B
2024-12-31$1.17B60