Stocks/Funds/CIK 1833486

Column Group LLC

long-term holderconcentrated
Quarterly 13F filings · Latest period 2026-03-31 · CIK 1833486
Assets
$101M
+127.7% YoY
Holdings
3
Lifetime alpha vs market
-23.83% annual
Average hold time
5.3 yr
median 5.5 yr

Quarterly history

Cum return -49% vs S&P +52% · α -101% lifetimeAUM $101M · peak $1.1BFlow $-12M (-14%)2020-122021-122022-122023-122024-122025-122026-03
AUM ($B)fundS&P 500(gap = α)/ Flow in/out

Behavior signals (lifetime)

Dip response
+3.32%
adds when stocks drop
when a holding falls −10%+
Middle response
-16.55%
baseline attrition
Rally response
-5.45%
trims into rallies
when a holding rises +10%+

Top positions · 3

Ticker$ value% portYoYHold time
SRZNSurrozen, Inc.$56M55.4%+149.8%4.8 yr
ORICORIC Pharmaceuticals, In$45M44.5%+127.1%5.5 yr
RVMDRevolution Medicines, In$0M0.0%+175.0%5.5 yr

Portfolio composition (YoY)

Industry mix
Biotechnology100.0%+3.7pp$101M
Country
US100.0%+3.7pp
Top 5: 100.0% · Top 10: 100.0% · Top 25: 100.0%

Winners

TickerPrev $PnLYoY %
SRZN$17M+0.03B149.8%
ORIC$20M+0.03B127.1%
RVMD$0M+0.00B175.0%

Losers

TickerPrev $PnLYoY %

Top buys this quarter · 1

SRZN Surrozen, Inc.+$2M

Top sells this quarter · 2

TNYA Tenaya Therapeutics, Inc.exit$7M
exit$0M

Quarterly history (TTM returns)

PeriodAUM# PosReturn (1yr)SPY (1yr)Alpha (1yr)Flow
2026-03-31$101M3+122.01%+17.59%+104.42%-0.01B
2025-12-31$83M5+5.18%+17.72%-12.54%+0.01B
2025-09-30$81M5-2.51%+17.52%-20.02%-0.01B
2025-06-30$66M5-29.09%+14.94%-44.03%+0.01B
2025-03-31$44M5-68.93%+8.30%-77.23%+0.01B
2024-12-31$56M5-24.68%+24.89%-49.57%-0.00B
2024-09-30$70M6+13.17%+36.04%-22.87%-0.00B
2024-06-30$71M6-9.78%+24.49%-34.27%-0.02B
2024-03-31$161M7+95.13%+29.62%+65.51%-0.08B
2023-12-31$151M6+25.01%+26.18%-1.16%-0.04B
2023-09-30$151M7-44.17%+21.57%-65.74%-0.06B
2023-06-30$258M7-51.08%+19.42%-70.51%-0.08B
2023-03-31$277M7-61.94%-7.82%-54.12%-0.02B
2022-12-31$300M7-43.86%+7.56%-51.43%+0.05B
2022-09-30$452M7-28.94%-4.93%-24.01%+0.12B
2022-06-30$470M7-4.65%-16.11%+11.46%-0.04B