Stocks/Funds/CIK 1687078

MPM BioImpact LLC

Quarterly 13F filings · Latest period 2026-03-31 · CIK 1687078
Assets
$1.29B
+122.6% YoY
Holdings
41
Lifetime alpha vs market
-6.91% annual
Average hold time
1.3 yr
median 0.8 yr

Quarterly history

Cum return +14% vs S&P +52% · α -38% lifetimeAUM $1.3B · peak $1.3BFlow $272M (+31%)2019-122020-122021-122022-122023-122024-122025-122026-03
AUM ($B)fundS&P 500(gap = α)/ Flow in/out

Behavior signals (lifetime)

Dip response
+2.08%
adds when stocks drop
when a holding falls −10%+
Middle response
-3.60%
baseline attrition
Rally response
+1.92%
adds into rallies
when a holding rises +10%+

Top positions · 30

Ticker$ value% portYoYHold time
$109M8.4%1.0 yr
CGEMCullinan Therapeutics, I$109M8.4%+87.7%5.3 yr
AKTSAktis Oncology, Inc.$87M6.7%0.3 yr
LQDALiquidia Corporation$53M4.1%+155.9%0.8 yr
ALMSAlumis Inc. Common Stock$53M4.1%+258.8%0.5 yr
EWTXEdgewise Therapeutics, I$52M4.0%+43.2%2.8 yr
RVMDRevolution Medicines, In$49M3.8%+175.0%4.8 yr
AGIOAgios Pharmaceuticals, I$44M3.4%+15.5%0.5 yr
CORTCorcept Therapeutics Inc$40M3.1%-64.7%0.3 yr
TRVITrevi Therapeutics, Inc.$39M3.0%+89.7%2.3 yr
DNTHDianthus Therapeutics, I$36M2.7%+362.6%0.3 yr
XENEXenon Pharmaceuticals In$34M2.6%+73.3%1.8 yr
MLTXMoonLake Immunotherapeut$34M2.6%-52.3%2.5 yr
TVTXTravere Therapeutics, In$34M2.6%+65.8%2.5 yr
EVMNEvommune, Inc.$33M2.6%0.5 yr

Portfolio composition (YoY)

Industry mix
Biotechnology76.5%+0.8pp$991M
Unknown13.7%+12.1pp$177M
Medical - Pharmaceuticals8.4%-1.6pp$109M
Medical - Diagnostics & Research1.4%-7.4pp$19M
Country
US78.4%-6.6pp
Unknown13.7%+12.1pp
CA2.6%+0.8pp
CH2.6%+0.5pp
NL1.7%
FR0.9%
Top 5: 31.6% · Top 10: 49.0% · Top 25: 82.7%

Winners

TickerPrev $PnLYoY %
CGEM$58M+0.05B87.7%
CNTX$9M+0.03B328.1%
RVMD$11M+0.02B175.0%
TRVI$22M+0.02B89.7%
STOK$5M+0.02B389.6%

Losers

TickerPrev $PnLYoY %
MLTX$12M-0.01B-52.3%

Top buys this quarter · 15

AKTS Aktis Oncology, Inc.new+$87M
CORT Corcept Therapeutics Incorporanew+$40M
DNTH Dianthus Therapeutics, Inc.new+$36M
EVMN Evommune, Inc.+$31M
MLTX MoonLake Immunotherapeutics+$28M
CYTK Cytokinetics, Incorporated+$20M
TVTX Travere Therapeutics, Inc.+$17M
XENE Xenon Pharmaceuticals Inc.+$6M
ABVX Abivax S.A.+$6M
ALLO Allogene Therapeutics, Inc.new+$5M

Top sells this quarter · 15

MDGL Madrigal Pharmaceuticals, Inc.exit$51M
PTCT PTC Therapeutics, Inc.exit$29M
VTYX Ventyx Biosciences, Inc.exit$23M
PTGX Protagonist Therapeutics, Inc.exit$21M
CRVS Corvus Pharmaceuticals, Inc.$21M
RCKT Rocket Pharmaceuticals, Inc.exit$6M
MAZE Maze Therapeutics, Inc.exit$2M
SRPT Sarepta Therapeutics, Inc.exit$2M
CLYM Climb Bio, Inc.$11M
ALMS Alumis Inc. Common Stock$23M

Quarterly history (TTM returns)

PeriodAUM# PosReturn (1yr)SPY (1yr)Alpha (1yr)Flow
2026-03-31$1.29B41+72.44%+17.59%+54.85%+0.27B
2025-12-31$874M38+23.43%+17.72%+5.71%+0.09B
2025-09-30$611M40-13.62%+17.52%-31.14%-0.06B
2025-06-30$577M44-21.54%+14.94%-36.49%-0.00B
2025-03-31$582M43-36.83%+8.30%-45.13%-0.01B
2024-12-31$704M47-0.51%+24.89%-25.39%+0.11B
2024-09-30$667M43+32.48%+36.04%-3.56%-0.01B
2024-06-30$644M44+6.14%+24.49%-18.35%+0.15B
2024-03-31$622M38+46.78%+29.62%+17.16%+0.06B
2023-12-31$427M32+0.09%+26.18%-26.09%-0.02B
2023-09-30$375M32-21.93%+21.57%-43.49%-0.05B
2023-06-30$497M34-6.37%+19.42%-25.79%+0.07B
2023-03-31$385M31-28.53%-7.82%-20.71%+0.04B
2022-12-31$385M33-7.25%+7.56%-14.81%-0.01B
2022-09-30$422M38+1.52%-4.93%+6.45%+0.06B
2022-06-30$360M37-15.66%-16.11%+0.46%+0.05B