Stocks/Funds/CIK 1582844

ACUTA CAPITAL PARTNERS, LLC

Quarterly 13F filings · Latest period 2026-03-31 · CIK 1582844
Assets
$141M
+79.9% YoY
Holdings
26
Lifetime alpha vs market
-11.93% annual
Average hold time
1.5 yr
median 0.8 yr

Quarterly history

Cum return -8% vs S&P +52% · α -61% lifetimeAUM $141M · peak $504MFlow $-23M (-16%)2016-062017-122019-062020-122022-062023-122025-062026-03
AUM ($B)fundS&P 500(gap = α)/ Flow in/out

Behavior signals (lifetime)

Dip response
-14.04%
trims when stocks drop
when a holding falls −10%+
Middle response
-4.36%
baseline attrition
Rally response
-3.02%
trims into rallies
when a holding rises +10%+

Top positions · 26

Ticker$ value% portYoYHold time
$27M19.5%2.5 yr
TERNTerns Pharmaceuticals, I$26M18.6%3.8 yr
WHWKWhitehawk Therapeutics I$12M8.4%+93.8%4.8 yr
TNGXTango Therapeutics, Inc.$9M6.6%+1427.0%0.5 yr
$8M5.8%1.5 yr
$7M4.8%0.5 yr
ERASErasca, Inc.$6M4.1%+1081.0%0.3 yr
$5M3.6%1.3 yr
OCULOcular Therapeutix, Inc.$5M3.6%+15.6%2.8 yr
CMPXCompass Therapeutics, In$4M3.2%+178.4%0.8 yr
NERVMinerva Neurosciences, I$4M3.0%+254.7%0.5 yr
MLTXMoonLake Immunotherapeut$4M2.5%-52.3%0.8 yr
ARGXargenx SE$3M2.4%+23.4%5.5 yr
$3M1.9%1.3 yr
RVMDRevolution Medicines, In$3M1.8%+175.0%2.5 yr

Portfolio composition (YoY)

Industry mix
Biotechnology62.3%-4.7pp$88M
Unknown37.7%+8.7pp$53M
Country
US57.3%-4.6pp
Unknown37.7%+8.7pp
CH2.5%
NL2.4%-2.9pp
Top 5: 58.8% · Top 10: 78.0% · Top 25: 99.7%

Winners

TickerPrev $PnLYoY %
WHWK$6M+0.01B93.8%
RVMD$2M+0.00B175.0%
OCUL$9M+0.00B15.6%
ARGX$4M+0.00B23.4%

Losers

TickerPrev $PnLYoY %

Top buys this quarter · 11

ERAS Erasca, Inc.new+$6M
TNGX Tango Therapeutics, Inc.+$3M
MLTX MoonLake Immunotherapeutics+$2M
RVMD Revolution Medicines, Inc.+$2M
IDYA IDEAYA Biosciences, Inc.+$1M
TRDA Entrada Therapeutics, Inc.new+$1M
new+$0M
+$0M
new+$0M
+$0M

Top sells this quarter · 15

JAZZ Jazz Pharmaceuticals plcexit$5M
OCUL Ocular Therapeutix, Inc.$4M
AMLX Amylyx Pharmaceuticals, Inc.$3M
DNTH Dianthus Therapeutics, Inc.exit$1M
CMPX Compass Therapeutics, Inc.$1M
ARGX argenx SE$0M
TSHA Taysha Gene Therapies, Inc.$0M
DSGN Design Therapeutics, Inc.$1M
UTHR United Therapeutics Corporatio$1M
LBRX LB Pharmaceuticals Inc Common $1M

Quarterly history (TTM returns)

PeriodAUM# PosReturn (1yr)SPY (1yr)Alpha (1yr)Flow
2026-03-31$141M26+90.94%+17.59%+73.35%-0.02B
2025-12-31$143M29+41.79%+17.72%+24.07%+0.03B
2025-09-30$91M27+7.72%+17.52%-9.79%-0.00B
2025-06-30$68M27-10.09%+14.94%-25.03%-0.01B
2025-03-31$78M32-17.84%+8.30%-26.14%-0.00B
2024-12-31$92M38+13.88%+24.89%-11.01%-0.01B
2024-09-30$116M40+27.46%+36.04%-8.58%-0.01B
2024-06-30$114M31+13.23%+24.49%-11.26%-0.03B
2024-03-31$152M32+21.85%+29.62%-7.77%-0.06B
2023-12-31$177M37-10.46%+26.18%-36.64%+0.04B
2023-09-30$138M42-15.33%+21.57%-36.90%-0.01B
2023-06-30$148M35-33.90%+19.42%-53.32%+0.02B
2023-03-31$128M33-52.11%-7.82%-44.30%-0.01B
2022-12-31$163M34-3.49%+7.56%-11.06%-0.05B
2022-09-30$225M46-21.58%-4.93%-16.65%+0.08B
2022-06-30$179M41-26.78%-16.11%-10.67%+0.02B