Stocks/PLRX

PLRX

Pliant Therapeutics, Inc.
Healthcare·Biotechnology
$1.26
$78M market cap
Revenue
$0.0M
Free Cash Flow
$-37.0M
Rev Growth
+0.0%
FCF Margin
0.0%
P/FCF
--
EV/FCF
--
Fwd EV/EBITDA
--
Fair Value
--
Upside
--

Pliant Therapeutics, Inc., a clinical stage biopharmaceutical company, discovers, develops, and commercializes novel therapies for the treatment of fibrosis and related diseases in the United States. Its lead product candidate is PLN-74809, an oral small-molecule dual selective inhibitor of avß6 and avß1 integrins, which is in three Phase 2a trials. The company also develops PLN-1474, a small-molecule selective inhibitor of avß1, which completed Phase 1 clinical trial for the treatment of liv

2-Year Price History

$1.21-89.1%
$2.0$4.0$6.0$8.0$10$12$14volJun 24Oct 24Jan 25May 25Sep 25Jan 26May 26

Quarterly Financials & Projections

Quarterly Waterfall ($ M)
PeriodRevEBITDAOpInNIOCFFCFCapExCashDebtSharesROICIntCovEV/EBITDA
Act2026-Q10.0-21.5-21.8-20.0-19.2-19.2-0.0170.928.861.8-123.1%----
Act2025-Q40.0-23.1-23.6-23.6-17.8-17.8-0.0190.929.161.4-107.2%-169.7x--

Valuation & Metrics

Market Stats

Price$1.26
Market Cap$78M
Enterprise Value$-64M
P/S Ratio0.0x
P/FCF--
EV/FCF--
FCF Margin (TTM)0.0%
FCF Yield-47.4%
Dividend Yield (TTM)--
Annual Dilution0.0%
CurrencyUSD

TTM Financial Snapshot

Revenue$0.0M
Net Income$-43.6M
Free Cash Flow$-37.0M

Revenue Growth (YoY)+0.0%
EBITDA Margin0.0%
Net Margin0.0%
FCF Margin0.0%
CapEx % of Revenue0.0%
SBC % of Revenue0.0%
ROIC-115.2%
WC Change % Rev0.0%
Interest Coverage-327.8x

Forward Outlook & Risk

Short Interest

Short % of Float--
Short Shares3.4M
Days to Cover5.3
Change (vs Prior)-5.8%
Need at least 2 settlement dates for chart

Employees

Headcount171
Revenue / Employee$0
Gross Profit / Employee$-1,544

Cash Runway

55.4months
WATCH

Institutional Ownership

Headline & net flow

NEUTRAL
Net flow · still filing
No float data — flow unavailable.

Ownership composition

Active
73.0%(-7.5% YoY)
76 filers
hedge / family / endowment
Retail funds
Fidelity, Schwab, 401(k)
Passive
8.1%(-13.6% YoY)
10 filers
Vanguard, iShares, SPDR
Market makers
0.7%(+0.2% YoY)
4 filers
Citadel, Susquehanna
Insiders
Form 4 — latest per insider
0%25%50%75%100%2022-062023-032023-122024-092025-062026-03
ActiveRetail fundsPassiveMarket makersRetail direct

Top holders

Fund$ valueCost basisΔ QoQΔ YoYα lifeFund AUM
TANG CAPITAL MANAGEMENT LLC$7.7M$1.35+$0+$180K-5.4%$1.93B
CITADEL ADVISORS LLC$4.1M$7.01+$811K+$4.1M-0.4%$138.22B
Blue Owl Capital Holdings LP$3.7M$17.06+$0+$0-1.1%$372M
ADAR1 Capital Management, LLC$3.3M$2.15+$3.2M+$3.3M+8.4%$1.64B
ACADIAN ASSET MANAGEMENT LLC$3.0M$1.37+$65K+$1.5M-0.5%$70.48B
VANGUARD CAPITAL MANAGEMENT LLCPassive$3.0M$1.26+$3.0M+$3.0M$4.04T
TWO SIGMA INVESTMENTS, LP$2.8M$5.34+$1.6M+$2.5M-0.9%$117.03B
Monaco Asset Management SAM$2.4M$1.21+$0+$2.4M+1.9%$315M
RENAISSANCE TECHNOLOGIES LLC$2.3M$3.54+$1.0M+$2.1M+1.2%$63.91B
Prosight Management, LP$2.1M$1.23+$141K+$1.7M-16.0%$610M
Woodline Partners LP$2.1M$2.33−$453K−$1.1M-0.1%$26.43B
BML Capital Management, LLC$1.9M$1.22+$0+$1.9M-1.6%$155M
Peapod Lane Capital LLC$1.6M$1.31+$507K+$797K+0.0%$122M
MILLENNIUM MANAGEMENT LLC$1.5M$5.17+$972K+$1.5M-0.5%$127.40B
BlackRock, Inc.Passive$1.4M$11.05+$29K−$5.2M-0.2%$5.69T
UBS Group AG$1.3M$5.38−$6K−$2.0M-0.3%$562.11B
MARSHALL WACE, LLP$1.3M$2.97−$106K+$992K+0.6%$92.71B
Eversept Partners, LP$1.1M$6.91+$62K+$1.1M-0.3%$1.52B
JPMORGAN CHASE & CO$1.0M$2.91−$442K+$447K-0.2%$1.47T
Redmile Group, LLC$973K$18.85−$1.1M−$1.6M-5.7%$1.51B
Cost basis is a volume-weighted estimate from accumulation periods within our 13F history; holders who built their position before our window started will show a stale basis. % above the cost basis is the unrealized gain at the current price.

Trading behavior

Smart-money alpha (lifetime, %/qtr)BULLISH
Holders
-1.38%
avg per quarter
Holders (ex-self)
-1.25%
excl. this stock
Buyers (this Q)
+1.69%
36 buyers · $0.01B in
Sellers (this Q)
-0.85%
28 sellers · $0.01B out
alpha coverage: 94% of $ has a lifetime-alpha record
Holder behavior on this stocksource: stock
On big dips (−10%+)
-14.0%
how holders react when this stock falls
On quiet Qs
+0.3%
−10% to +10% baseline
On rallies (+10%+)
-5.6%
how they react when this stock rises
Holders' portfolio flow this Q
+3.7%
inflows — adds are organic
Sellers' portfolio flow this Q
+4.7%
Sellers grew AUM elsewhere — opinionated cut of this stock.
▸ Compare to holder-profile behavior (across all their stocks)
Holder dip (any stock)
-2.3%
Holder mid (any stock)
-4.9%
Holder rally (any stock)
-13.0%

Top Holders Over Time

5-year share-count history (top 10 holders by peak, incl. exited) + price

06.3M12.6M18.9M25.1M$1.16$7.52$14$20$272021-062022-062023-062024-062025-062026-03
hover the chart for per-quarter detailprice (right axis)
TRV GP III, LLCFMR LLC524Deep Track Capital, LPRedmile Group, LLC772KCHI Advisors LLCEVENTIDE ASSET MANAGEMENT, LLCAvidity Partners Management LPPRICE T ROWE ASSOCIATES INC /MD/First Light Asset Management, LLCLaurion Capital Management LP413K

Analyst Coverage

Analyst Coverage
Price Targets
Last Quarter (1 analysts)$3.0013810.0%
Last Year (1 analysts)$3.0013810.0%
Current Price$1.26
Analyst Ratings
8
7
Buy: 8Hold: 7Sell: 1Consensus: Buy

Corporate

Insider Trading (last 12mo)

Open-market only (Form 4 P-Purchase + S-Sale). Excludes grants, option exercises, tax withholding, gifts.
Officers & directors
Buys ($, 12mo)
$0
0 txns · 0 insiders · 0 sh
Sells ($, 12mo)
$164K
4 txns · 4 insiders · 127,828 sh
Recent transactions
DateSideInsiderTitleSharesPriceDollarsOwned $
2026-01-20SELLCheung Lilyofficer: Chief Human Resource Officer7,534$1.28$10K$57K
2026-01-20SELLCoulie Bernarddirector, officer: President and CEO89,375$1.28$114K$647K
2026-01-20SELLCummings Keith Lamontofficer: Chief Financial Officer24,002$1.28$31K$380K
2026-01-20SELLKuo Minnieofficer: Chief Operating Officer6,917$1.28$9K$48K

Order Flow (FINRA, ~3w lag)

35.1%retail-8.1pp
19.5%dark+4.7pp
week of 2026-04-13
0%20%40%60%24-1125-0225-0525-0825-1126-0226-04retail (non-ATS)dark (ATS)
Off-exchange volume from FINRA. Retail = non-ATS (wholesaler PFOF + broker internalization). Dark = ATS (dark-pool crossing networks, institutional). Lit-exchange = remainder.

Filing Risk Analysis

Filing Risk Scores

PLIANT THERAPEUTICS, INC.: Defensive Moats and Massive Layoffs in a Race Against Liquid Exhaustion

Overall Risk
7/10
Fraud
2/10
Dilution
8/10
Insolvency
7/10
Earnings Overstated
2/10
Hidden Liabilities
4/10
Legal
4/10
Audit Warnings
3/10
Hidden Upside
4/10
Contextually Acceptable
6/10