Stocks/Funds/CIK 1917529

Atlas Venture Life Science Advisors, LLC

long-term holderconcentrated
Quarterly 13F filings · Latest period 2026-03-31 · CIK 1917529
Assets
$790M
+51.4% YoY
Holdings
6
Lifetime alpha vs market
+6.83% annual
Average hold time
3.1 yr
median 3.0 yr

Quarterly history

Cum return +98% vs S&P +52% · α +46% lifetimeAUM $790M · peak $1.1BFlow $-110M (-13%)2021-122022-092023-062024-032024-122025-092026-03
AUM ($B)fundS&P 500(gap = α)/ Flow in/out

Behavior signals (lifetime)

Dip response
+0.38%
adds when stocks drop
when a holding falls −10%+
Middle response
-2.09%
baseline attrition
Rally response
-3.96%
trims into rallies
when a holding rises +10%+

Top positions · 6

Ticker$ value% portYoYHold time
KYMRKymera Therapeutics, Inc$381M48.3%+204.3%4.5 yr
DYNDyne Therapeutics, Inc.$166M21.0%+73.3%4.5 yr
SIONSionna Therapeutics, Inc$120M15.2%+283.3%1.3 yr
IRONDisc Medicine, Inc.$97M12.3%+28.8%3.5 yr
QTTBQ32 Bio Inc.$13M1.7%+289.1%2.3 yr
KRROKorro Bio, Inc.$13M1.6%-35.0%2.5 yr

Portfolio composition (YoY)

Industry mix
Biotechnology100.0%+0.6pp$790M
Country
US100.0%+0.6pp
Top 5: 98.4% · Top 10: 100.0% · Top 25: 100.0%

Winners

TickerPrev $PnLYoY %
KYMR$134M+0.27B204.3%
SION$39M+0.11B283.3%
DYN$96M+0.07B73.3%
IRON$118M+0.03B28.8%
QTTB$3M+0.01B289.1%

Losers

TickerPrev $PnLYoY %
KRRO$20M-0.01B-35.0%

Top buys this quarter · 0

No buys this quarter

Top sells this quarter · 3

GBIO Generation Bio Co.exit$0M
DAWN Day One Biopharmaceuticals, Inexit$137M
KYMR Kymera Therapeutics, Inc.$363M

Quarterly history (TTM returns)

PeriodAUM# PosReturn (1yr)SPY (1yr)Alpha (1yr)Flow
2026-03-31$790M6+120.74%+17.59%+103.14%-0.11B
2025-12-31$865M8+30.65%+17.72%+12.93%-0.10B
2025-09-30$753M9-19.05%+17.52%-36.57%-0.17B
2025-06-30$662M11-28.19%+14.94%-43.13%+0.04B
2025-03-31$522M13-48.16%+8.30%-56.46%+0.02B
2024-12-31$820M13+27.02%+24.89%+2.14%-0.04B
2024-09-30$1.08B14+111.61%+36.04%+75.57%-0.09B
2024-06-30$950M15+47.36%+24.49%+22.87%+0.02B
2024-03-31$1.08B16+84.31%+29.62%+54.69%-0.18B
2023-12-31$840M16+11.02%+26.18%-15.16%-0.01B
2023-09-30$646M15-6.37%+21.57%-27.94%-0.04B
2023-06-30$804M15+32.18%+19.42%+12.76%+0.01B
2023-03-31$739M16-6.02%-7.82%+1.80%-0.02B
2022-12-31$830M17+11.47%+7.56%+3.91%-0.18B
2022-09-30$906M17+20.93%-4.93%+25.86%+0.18B
2022-06-30$598M16-23.32%-16.11%-7.21%-0.01B