Stocks/Funds/CIK 1274413

SECTORAL ASSET MANAGEMENT INC

long-term holder
Quarterly 13F filings · Latest period 2026-03-31 · CIK 1274413
Assets
$117M
-7.8% YoY
Holdings
76
Lifetime alpha vs market
-2.86% annual
Average hold time
4.6 yr
median 4.0 yr

Quarterly history

Cum return +35% vs S&P +52% · α -17% lifetimeAUM $117M · peak $1.4BFlow $-6M (-5%)2016-062017-122019-062020-122022-062023-122025-062026-03
AUM ($B)fundS&P 500(gap = α)/ Flow in/out

Behavior signals (lifetime)

Dip response
-8.37%
trims when stocks drop
when a holding falls −10%+
Middle response
-9.10%
baseline attrition
Rally response
-19.82%
trims into rallies
when a holding rises +10%+

Top positions · 30

Ticker$ value% portYoYHold time
EVMNEvommune, Inc.$14M11.5%0.5 yr
CTNMContineum Therapeutics, $10M8.1%+87.1%2.0 yr
$6M5.3%0.8 yr
LLYEli Lilly and Company$6M5.0%+12.2%9.8 yr
JNJJohnson & Johnson$4M3.8%+51.5%8.0 yr
GILDGilead Sciences, Inc.$4M3.5%+27.7%9.5 yr
UNHUnitedHealth Group Incor$4M3.4%-46.9%9.0 yr
AMGNAmgen Inc.$4M3.0%+16.5%7.0 yr
VRTXVertex Pharmaceuticals I$3M2.9%-7.9%9.5 yr
ARGXargenx SE$3M2.3%+23.4%5.5 yr
ABBVAbbVie Inc.$3M2.3%+7.3%6.5 yr
ABTAbbott Laboratories$3M2.2%-21.1%8.5 yr
MRKMerck & Co., Inc.$3M2.2%+38.9%9.3 yr
REGNRegeneron Pharmaceutical$2M2.1%+22.5%8.0 yr
ISRGIntuitive Surgical, Inc.$2M2.1%-6.9%4.3 yr

Portfolio composition (YoY)

Industry mix
Biotechnology49.9%-3.0pp$59M
Drug Manufacturers - General21.8%+0.8pp$26M
Medical - Devices11.4%+0.5pp$13M
Unknown6.1%+4.7pp$7M
Medical - Diagnostics & Research5.2%+0.6pp$6M
Medical - Healthcare Plans3.9%-2.5pp$5M
Medical - Healthcare Information Services1.2%+0.4pp$1M
Medical - Pharmaceuticals0.5%-0.1pp$1M
Country
US86.1%-4.9pp
Unknown6.1%+4.7pp
NL2.8%+0.8pp
DE2.3%+1.1pp
IE1.1%-1.3pp
GB0.9%+0.5pp
BE0.4%
FR0.3%
Top 5: 33.7% · Top 10: 49.0% · Top 25: 74.1%

Winners

TickerPrev $PnLYoY %
CTNM$6M+0.00B87.1%
JNJ$4M+0.00B51.5%
GILD$4M+0.00B27.7%
LLY$8M+0.00B12.2%
MRK$2M+0.00B38.9%

Losers

TickerPrev $PnLYoY %
UNH$7M-0.00B-46.9%
BSX$2M-0.00B-37.8%
ABT$2M-0.00B-21.1%
SYK$2M-0.00B-11.1%
VRTX$2M-0.00B-7.9%

Top buys this quarter · 15

GILD Gilead Sciences, Inc.+$1M
ARDX Ardelyx, Inc.new+$1M
BMY Bristol-Myers Squibb Company+$1M
ARGX argenx SE+$0M
AGMB AgomAb Therapeutics N.V. Amerinew+$0M
BSX Boston Scientific Corporation+$2M
BNTX BioNTech SE+$0M
SPRY ARS Pharmaceuticals, Inc.+$0M
UNH UnitedHealth Group Incorporate+$4M
ABVX Abivax S.A.new+$0M

Top sells this quarter · 15

AMGN Amgen Inc.$1M
VTYX Ventyx Biosciences, Inc.exit$1M
MDT Medtronic plc$1M
ABBV AbbVie Inc.$1M
CTNM Contineum Therapeutics, Inc. C$9M
LLY Eli Lilly and Company$1M
TECX Tectonic Therapeutic, Inc.$1M
SNDX Syndax Pharmaceuticals, Inc.$1M
FOLD Amicus Therapeutics, Inc.exit$1M
REGN Regeneron Pharmaceuticals, Inc$1M

Quarterly history (TTM returns)

PeriodAUM# PosReturn (1yr)SPY (1yr)Alpha (1yr)Flow
2026-03-31$117M76+44.06%+17.59%+26.47%-0.01B
2025-12-31$123M73+48.38%+17.72%+30.66%-0.05B
2025-09-30$160M81+24.45%+17.52%+6.93%-0.05B
2025-06-30$150M93-2.37%+14.94%-17.31%+0.03B
2025-03-31$127M83-3.34%+8.30%-11.64%-0.03B
2024-12-31$150M86+3.73%+24.89%-21.16%-0.01B
2024-09-30$169M90+23.89%+36.04%-12.15%-0.10B
2024-06-30$246M97+1.91%+24.49%-22.59%+0.01B
2024-03-31$254M92+18.04%+29.62%-11.58%-0.00B
2023-12-31$232M104+2.60%+26.18%-23.58%-0.34B
2023-09-30$514M123-6.66%+21.57%-28.23%-0.02B
2023-06-30$600M121+4.68%+19.42%-14.75%+0.04B
2023-03-31$520M118-17.58%-7.82%-9.76%+0.02B
2022-12-31$517M120+0.76%+7.56%-6.80%+0.01B
2022-09-30$508M109-0.40%-4.93%+4.52%+0.01B
2022-06-30$496M112-14.72%-16.11%+1.39%+0.02B