Stocks/Funds/CIK 1802630

Soleus Capital Management, L.P.

long-term holder
Quarterly 13F filings · Latest period 2026-03-31 · CIK 1802630
Assets
$2.47B
+104.0% YoY
Holdings
91
Lifetime alpha vs market
-3.34% annual
Average hold time
1.9 yr
median 1.3 yr

Quarterly history

Cum return +33% vs S&P +52% · α -19% lifetimeAUM $2.5B · peak $2.5BFlow $118M (+5%)2019-122020-122021-122022-122023-122024-122025-122026-03
AUM ($B)fundS&P 500(gap = α)/ Flow in/out

Behavior signals (lifetime)

Dip response
+2.76%
adds when stocks drop
when a holding falls −10%+
Middle response
-11.61%
baseline attrition
Rally response
-15.90%
trims into rallies
when a holding rises +10%+

Top positions · 30

Ticker$ value% portYoYHold time
KRYSKrystal Biotech, Inc.$298M12.1%+43.3%5.5 yr
CELCCelcuity Inc.$147M5.9%+1029.0%5.0 yr
TGTXTG Therapeutics, Inc.$134M5.4%-15.7%3.5 yr
PODDInsulet Corporation$118M4.8%-20.1%2.0 yr
NVCRNovoCure Limited$114M4.6%-38.8%5.5 yr
UTHRUnited Therapeutics Corp$111M4.5%+92.4%4.8 yr
$106M4.3%2.3 yr
VCELVericel Corporation$82M3.3%-27.9%3.5 yr
ALKSAlkermes plc$70M2.8%+7.1%1.3 yr
ANIPANI Pharmaceuticals, Inc$63M2.6%+14.9%1.8 yr
GMEDGlobus Medical, Inc.$63M2.5%+17.7%1.0 yr
GERNGeron Corporation$62M2.5%-6.3%1.3 yr
TWSTTwist Bioscience Corpora$58M2.4%+21.0%1.3 yr
EWTXEdgewise Therapeutics, I$46M1.9%+43.2%2.0 yr
BBNXBeta Bionics, Inc.$44M1.8%-18.1%1.3 yr

Portfolio composition (YoY)

Industry mix
Biotechnology57.3%+5.4pp$1.41B
Medical - Devices16.1%+3.0pp$397M
Unknown7.2%-1.6pp$176M
Drug Manufacturers - Specialty & Generic5.5%-2.4pp$135M
Medical - Instruments & Supplies4.6%-5.0pp$114M
Medical - Diagnostics & Research4.5%$111M
Medical - Healthcare Information Services1.8%$44M
Medical - Equipment & Services1.8%-1.7pp$44M
Drug Manufacturers - General1.0%-4.2pp$24M
Medical - Pharmaceuticals0.3%$8M
Country
US79.9%+9.0pp
Unknown7.2%-1.6pp
JE4.6%-3.5pp
IE3.7%
GB1.5%+1.0pp
FR1.1%-1.2pp
NL0.9%-2.9pp
CA0.8%-0.1pp
Top 5: 32.9% · Top 10: 50.4% · Top 25: 76.2%

Winners

TickerPrev $PnLYoY %
CELC$26M+0.27B1029.0%
UTHR$48M+0.04B92.4%
KRYS$80M+0.03B43.3%
AXGN$27M+0.02B79.1%
EDAP$14M+0.01B89.8%

Losers

TickerPrev $PnLYoY %
NVCR$98M-0.04B-38.8%
ORGO$54M-0.02B-45.1%
TGTX$112M-0.02B-15.7%
BMRN$76M-0.02B-20.1%
BBNX$42M-0.01B-18.1%

Top buys this quarter · 15

PODD Insulet Corporation+$87M
UTHR United Therapeutics Corporatio+$75M
VCEL Vericel Corporation+$57M
KRYS Krystal Biotech, Inc.+$55M
INDV Indivior Pharmaceuticals Incnew+$39M
PGNY Progyny, Inc.new+$35M
TGTX TG Therapeutics, Inc.+$30M
GERN Geron Corporation+$27M
ANIP ANI Pharmaceuticals, Inc.+$26M
ALKS Alkermes plc+$23M

Top sells this quarter · 15

FOLD Amicus Therapeutics, Inc.exit$75M
DXCM DexCom, Inc.$73M
CELC Celcuity Inc.$60M
BMRN BioMarin Pharmaceutical Inc.$38M
GSK GSK plcexit$35M
ERAS Erasca, Inc.exit$35M
ELVN Enliven Therapeutics, Inc.$31M
TWST Twist Bioscience Corporation$30M
NBIX Neurocrine Biosciences, Inc.exit$23M
TFX Teleflex Incorporatedexit$23M

Quarterly history (TTM returns)

PeriodAUM# PosReturn (1yr)SPY (1yr)Alpha (1yr)Flow
2026-03-31$2.47B91+43.39%+17.59%+25.80%+0.12B
2025-12-31$2.35B92+33.00%+17.72%+15.28%-0.01B
2025-09-30$1.86B85-0.91%+17.52%-18.42%+0.14B
2025-06-30$1.39B92-9.18%+14.94%-24.12%+0.28B
2025-03-31$1.21B72-6.65%+8.30%-14.96%+0.00B
2024-12-31$1.30B79+16.20%+24.89%-8.69%+0.16B
2024-09-30$1.20B85+37.09%+36.04%+1.06%-0.07B
2024-06-30$1.13B91+4.75%+24.49%-19.74%+0.06B
2024-03-31$1.13B89+14.99%+29.62%-14.63%+0.10B
2023-12-31$896M72+5.72%+26.18%-20.45%-0.20B
2023-09-30$987M89+4.59%+21.57%-16.98%+0.21B
2023-06-30$900M101+17.11%+19.42%-2.31%+0.07B
2023-03-31$807M76-13.68%-7.82%-5.86%+0.07B
2022-12-31$692M71+10.33%+7.56%+2.77%-0.12B
2022-09-30$735M75-3.23%-4.93%+1.69%+0.14B
2022-06-30$618M69-23.85%-16.11%-7.74%+0.12B